30 Most Poisonous Animals In The World (Never touch or eat them 2023)

Nature is full of surprises, but it can also be extremely deadly. There are many creatures on the planet that are exceedingly poisonous and can kill people.

These species are not to be trifled with, from microscopic insects to enormous beasts. In this article, we will look at the 30 most toxic animals on the planet, which you should never touch or eat.

We’ll look at the science underlying their poison, habitats, and hunting strategies. So buckle up and prepare to learn about some of the world’s deadliest beasts.

30 Most Poisonous Animals Worldwide

1. Box Jellyfish

Box Jellyfish
Box Jellyfish
Scientific Name Chironex fleckeri
Size Up to 30 cm bell diameter, up to 3 m long tentacles
Habitat Coastal waters, estuaries
Location Northern Australia, Southeast Asia, Pacific islands
Danger Level Very dangerous, poisonous
Number of Deaths in a year  Estimated 20-40 deaths per year

The medusa form of a box jellyfish gets its name from its squarish, box-like bell. A short pedalium or stalk hangs from each of the four bottom corners of this, bearing one or more long, slender, hollow tentacles.

When the bell pulsates, the rim of the bell folds inwards to form a shelf known as a velarium, which confines the aperture and creates a forceful jet. As a result, box jellyfish can travel faster than other jellyfish, reaching speeds of up to 6 meters per minute.

2. Marbled Cone Snail

Marbled Cone Snail
Marbled Cone Snail
Scientific Name Conus marmoreus
Size Up to 7 cm
Habitat Tropical coral reefs
Location Indo-Pacific region
Danger Level Highly poisonous
Number of Deaths in a year  Estimated around 10 deaths per year

These snails are indeed gorgeous, but they are very dangerous. A single drop of this snail’s venom is capable of killing 20 adult people! While some animals’ poison is more lethal, none can do as much damage with as little.

A cone snail sting can cause tingling, swelling, numbness, and excruciating agony. Symptoms in severe cases include respiratory paralysis, visual impairment, and muscle paralysis.

The idea that you may feel the effects immediately but that they may take days to manifest does not set my mind at ease!

3. Blue-Ringed Octopus

Blue-ringed octopus
Blue-ringed octopus | Credit: Rickard Zerpe (@flickr)
Scientific Name Hapalochlaena lunulata
Size Up to 8 inches (20 cm) in length
Habitat Shallow coral reefs and tide pools
Location Found in the Pacific and Indian Oceans, including Australia, Japan, and the Philippines
Danger Level Highly poisonous, potentially lethal
Number of Deaths in a year  Estimated around 4-7 deaths per year

As a warning signal, the octopus normally flashes its iridescent rings for about a third of a second.

To see if blue-ringed octopuses might generate their own blue iridescence, scientists immersed octopus samples in a variety of substances known to impact chromatophores and iridophores.

It was discovered that none of the chemicals utilized had any effect on the octopuses’ capacity to make blue rings.

4. Stonefish

Scientific Name Synanceia spp.
Size Up to 30 cm (11.8 in)
Habitat Coral reefs, rocky areas
Location The Indo-Pacific region, Australia, Japan
Danger Level Extremely poisonous
Number of Deaths in a year  Estimated around 3-5 deaths per year

Synanceia poison contains verrucotoxin (VTX), a proteinaceous toxin that affects Ca2+ channel function via the -adrenoceptor-cAMP-PKA pathway.

In humans, stings can cause severe pain, respiratory weakness, cardiovascular damage, convulsions, and paralysis and can even result in death. Stonefish stings are exceedingly painful and can be fatal.

The two most commonly advised therapies are heat therapy to the affected area and antivenom. Heated water of at least 45 °C (113 °F) administered to the damaged area denatures stonefish poison while causing minimal discomfort to the victim.

5. Irukandji Jellyfish

Irukandji jellyfish
Irukandji jellyfish | Credit: Brian Cassey/AP (thecut)
Scientific Name Carukia barnesi
Size Up to 2.5 cm in bell diameter
Habitat Tropical waters
Location Northern Australia, Thailand, Malaysia, Philippines, Vietnam, and some Pacific islands
Danger Level Extremely dangerous
Number of Deaths in a year  Estimated around 1-2

Unlike most jellyfish, which only have stingers on their tentacles, the Irukandji possesses stingers on both sides of its bell. Biologists have yet to determine the function of this distinct feature.

According to the theory, the characteristic aids the jellyfish in catching its meal of small fish. Irukandji jellyfish may inject poison and fire stingers from the tips of their tentacles.

The stings of the Irukandji jellyfish are so painful that they can induce fatal brain haemorrhages and send 50-100 individuals to the hospital.

6. Grey Side Gilled Sea Slug

Grey Side Gilled Sea Slug
Grey Side Gilled Sea Slug | Credit: Auckland War Memorial Museum – Tāmaki Paenga Hira (aucklandmuseum)
Scientific Name Pleurobranchaea maculata
Size up to 10 cm
Habitat a wide range of marine coastal habitats including rocky coastline
Location New Zealand, south eastern Australia, Japan, and Sri Lanka
Danger Level Highly toxic
Number of Deaths in a year  Death of several dogs per year

Grey Side Gilled Sea Slug is a species of brown sea slug that is highly poisonous in nature. These slugs contain slugs contained tetrodotoxin (TTX), a potent neurotoxin with no known antidote that can kill humans. Every year, many dogs die due to Grey Side Gilled Sea Slug on Auckland beaches.

7. Harlequin Frog

Scientific Name Oophaga histrionica
Size 2.5 to 5.5 cm (1 to 2.2 in)
Habitat Moist forests and streamsides
Location Central and South America
Danger Level Highly toxic
Number of Deaths in a year  No information

These moderate to moderately hazardous chemicals attach to a regulatory location on the delta subunit of the ion channel complex and operate as powerful noncompetitive antagonists of nicotinic acetylcholine receptors.

They also have some affinity for sodium and potassium channels, however, this attraction is much weaker.

Histrionicotoxins and their homologues are difficult to synthesise and have been the focus of numerous attempts.

8. Blue Dart Frog

Blue Dart Frog
Blue Dart Frog
Scientific Name Dendrobates tinctorius
Size 2-5 cm
Habitat Rainforest
Location South America
Danger Level Highly toxic
Number of Deaths in a year  No information

In the wild, the frog has an average lifespan of five to seven years. Predators are warned off by its brilliant blue skin, which is usually darker around its limbs and tummy. The glands of deadly alkaloids have discovered a defence mechanism against prospective predators.

These toxins paralyse and, in certain cases, kill the predator. The black dots are unique to each frog, allowing them to be identified. This frog has a characteristic hunched-back posture.

Each foot contains four toes, each with a flattened tip and a suction cup pad for grip. Females have spherical toe tips, but males have heart-shaped tips.

9. Pufferfish

Scientific Name Tetraodontidae
Size 3 inches to 3 feet
Habitat Tropical and subtropical waters
Location Northern and Southern US
Danger Level Extremely dangerous
Number of Deaths in a year  1-2 deaths on average

They are physically similar to porcupinefish, which have enormous exterior spines (unlike the thinner, hidden spines of the Tetraodontidae, which are only visible when the fish have puffed up).

The scientific name relates to the four massive teeth fused into an upper and lower plate, which are employed to shatter the hard shells of their native prey, crustaceans and mollusks.

The majority of pufferfish species are deadly, and some are among the world’s most dangerous vertebrates.

10. Lionfish

Scientific Name Pterois volitans
Size Up to 15 inches
Habitat Coral reefs, rocky crevices, and mangroves
Location Native to the Indo-Pacific but invasive in the Caribbean and Gulf of Mexico
Danger Level High
Number of Deaths in a year  1-2 deaths on average

Lionfish are noted for having poisonous fin rays, which make them dangerous to both other marine species and humans.

Pterois poison was found to have negative inotropic and chronotropic effects in both frog and clam hearts, as well as a depressed effect on rabbit blood pressure. These findings are assumed to be the outcome of nitric oxide production.

Pterois poison can produce systemic symptoms in humans, such as pain, nausea, vomiting, fever, headache, numbness, paresthesia, diarrhoea, sweating, transient limb paralysis, respiratory insufficiency, heart failure, convulsions, and even death.

Fatalities are more prevalent in infants, the elderly, and people who are allergic to the poison.

11. Portuguese man o’ war

Portuguese man o' war
Portuguese man o’ war
Scientific Name Physalia physalis
Size Up to 30 cm long tentacles, with a float that can be up to 15 cm long.
Habitat Ocean surface waters
Location Tropical and subtropical waters around the world, including the Atlantic, Pacific, and Indian Oceans
Danger Level High
Number of Deaths in a year  No information

The Portuguese man o’ war is a prominent member of the neuston, a community of creatures living on the ocean’s surface. It has several poisonous tiny nematocysts that inflict a painful sting strong enough to kill fish and has been reported to kill humans on occasion.

Although it appears to be a jellyfish, the Portuguese man of war is actually a siphonophore. It, like all siphonophores, is a colonial organism composed of many smaller units known as zooids.

12. Nudibranch

Scientific Name Nudibranchia
Size 2 cm to 60 cm
Habitat Marine, usually benthic
Location Found in oceans worldwide
Danger Level High
Number of Deaths in a year  No information

Nudibranchs have a wide range of body forms, but because they are opisthobranchs, unlike the majority of other gastropods, they appear to be bilaterally symmetrical externally (but not internally) due to secondary detorsion.

The male and female genital openings are on the right side of the body in all nudibranchs, indicating their asymmetrical ancestry. The mantle cavity is absent.

Several species have cerata, or poisonous appendages, on their flanks to ward off predators. Many also have a straightforward gut and a radulated mouth.

13. Flamboyant Cuttlefish

Flamboyant Cuttlefish
Flamboyant Cuttlefish
Scientific Name Metasepia pfefferi
Size Up to 8cm in length
Habitat Shallow tropical reef environments
Location Indo-Pacific region
Danger Level Moderate to humans
Number of Deaths in a year  No information

During the day, the species is active and has been recorded hunting fish and crabs. It stalks its prey using intricate and varied camouflage. This species’ usual base colour is dark brown.

Those who have been disturbed or attacked rapidly change color to a pattern of black, dark brown, and white with yellow patches around the mantle, arms, and eyes. To fend off potential predators, the arm tips are frequently painted bright red.

14. Greater Soapfish

Scientific Name Rypticus saponaceus
Size Up to 61 cm (24 in)
Habitat Coral reefs, rocky areas, and sandy bottoms
Location Western Atlantic: from Florida to Brazil
Danger Level Moderate to humans
Number of Deaths in a year  No information

A few morphological characteristics, such as the absence of anal fin spines, separate the genus from the remainder of the Serranidae.

It also only has two to four dorsal fin spines, whereas other serranids have more. The lower jaw protrudes, and the mouth is big.

The color varies, but a brown stripe runs from the mouth to the front of the dorsal fin in most cases.

15. Smooth Trunkfish

Smooth Trunkfish
Smooth Trunkfish
Scientific Name Lactophrys triqueter
Size Up to 12 inches
Habitat Coral reefs and rocky areas
Location Western Atlantic Ocean
Danger Level Moderate to humans
Number of Deaths in a year  Around 2 on average

The smooth trunkfish is typically solitary; however, it does occasionally congregate in small groups. It expels a jet of water from its protuberant lips, which disturbs the sandy seabed and reveals any shallowly buried benthic creatures.

Little mollusks, polychaete worms, acorn worms, peanut worms, tiny crustaceans, sponges, and tunicates are among its favorite foods.

Care is advised, however, because it creates a poisonous chemical, ostracitoxin, in skin mucous secretions.

16. Yellowtail Amberjack

Yellowtail Amberjack
Yellowtail Amberjack
Scientific Name Seriola lalandi
Size Up to 4 feet (1.2 m)
Habitat Shallow and deep waters
Location Pacific and Indian Oceans, Southern Ocean
Danger Level Moderate
Number of Deaths in a year  No information

They thrive on coastal reefs and sandy environments, sometimes reaching estuaries. They have been collected at depths of nearly 300 meters.

In shoals of several hundred fish, 7-kg juveniles have been seen. Larger fish are found around deep reefs and offshore islands.

17. Smooth Toadfish

Scientific Name Lagocephalus laevigatus
Size Up to 30 cm (12 in)
Habitat Shallow waters, sandy or rocky bottoms
Location Eastern Atlantic Ocean, Mediterranean Sea
Danger Level Poisonous, extremely deadly
Number of Deaths in a year  Around 3 in Average

The smooth toadfish has a small mouth and chin. The round eyes are adnate (unable to rotate), with their upper border level with the back profile and their lower border much above the mouth.

The nasal organs are two tiny papillae in front of the eyes. The fish’s back apertures are closed by flaps on the walls closest to its midline.

18. Xanthid Crab

Xanthid Crab
Xanthid Crab
Scientific Name Xanthidae spp.
Size 1-3 inches
Habitat Saltwater
Location USA, Singapore
Danger Level Highly Poisonous
Number of Deaths in a year  No information

The highly toxic xanthid crabs are frequently vividly colored and carry toxins that cannot be eliminated by cooking and for which there is no known cure.

The toxins, which are related to those generated by puffer fish like tetrodotoxin and saxitoxin, may be created by bacteria of the genus Vibrio that coexist with crabs in a symbiotic relationship.

19. Giant Moray Eel

Giant Moray Eel
Giant Moray Eel
Scientific Name Gymnothorax javanicus
Size Up to 3 meters
Habitat Coral reefs, rocky crevices
Location The Indo-Pacific region, Red Sea, East Africa, Australia, Japan
Danger Level High
Number of Deaths in a year  No information

It is the largest moray eel in terms of body mass, although the slender giant moray is the biggest in terms of body length. The enormous moray hunts its victim within the reef at night and consumes meat.

It has a reputation for cooperating in hunting with roaming coral groupers (Plectropomus pessuliferus).

These two fish species hunt cooperatively: The grouper will consume the prey that the eel chases up and out of the reef as it hunts there.

Similar to how a grouper foraging over a reef may induce prey to try to find cover there, where a moray might ambush them.

20. Striped Pyjama Squid

Striped Pyjama Squid
Striped Pyjama Squid | Credit: Scubagirl85 (commons.wikimedia) (CC BY-SA 3.0)
Scientific Name Sepioloidea lineolata
Size Up to 3 cm in length
Habitat Benthic (bottom-dwelling) in shallow waters
Location The Indo-Pacific region, from the east coast of Africa to Australia and Japan
Danger Level Moderate
Number of Deaths in a year  No information

The striped pyjama squid may conceal itself by altering its appearance because it is a non-nautiloid cephalopod. When it is attacked or has to blend in with its surroundings, the squid will turn a dark brown or purple color.

Eight arms and two feeding tentacles are features of the Sepioloidea lineolata. It is tiny and has a rounded shell.

Moreover, Sepioloidea lineolata have glands beneath their bodies that can release a toxic slime once a predator attacks the squid. Many different proteins and poisons are present in the squid’s slime.

21. Dyeing Dart Frog 

Dyeing Dart Frog 
Dyeing Dart Frog
Scientific Name Dendrobates tinctorius
Size 1.5-5 cm
Habitat Rainforests
Location South America (French Guiana, Suriname, Brazil)
Danger Level Moderate
Number of Deaths in a year  No information

The frog uses these pumiliotoxins and allopumiliotoxins to defend itself.

Pumiliotoxins are less potent than the batrachotoxins generated by Phyllobates species and their derivative allopumiliotoxins, but they are still harmful enough to deter most animals from eating them.

When D. tinctorius frogs are handled harshly, the toxins result in pain, cramping, and stiffness.

22. Strawberry Poison Dart Frog

Strawberry Poison Dart Frog
Strawberry Poison Dart Frog
Scientific Name Oophaga pumilio
Size 1-2 inches (2.5-5 cm)
Habitat Tropical Rainforest
Location Central America, Caribbean
Danger Level Mildly Toxic
Number of Deaths in a year  No information

The strawberry poison dart frog (Oophaga pumilio) is the most poisonous member of its genus, Oophaga, albeit it is not the most poisonous poison frog overall.

Also, you should use caution around this species because, at least initially, you might not be aware of what you’re looking at.

Although the predominant hue of this species is bright red, there are between 15 and 30 other color variants that range from red to blue to green with black spots. This species’ eye-catching hues act as a toxicology alert.

23. Lovely Poison Frog

Lovely Poison Frog
Lovely Poison Frog
Scientific Name Phyllobates lugubris
Size 4.5 cm (max)
Habitat Rainforests
Location Central America, Costa Rica, southeastern Nicaragua, and central Panama.
Danger Level Mildly Toxic
Number of Deaths in a year  No information

The Phyllobates lugubris, a lovely poison frog, is also known as the striped poison dart frog. This member of the Phyllobates genus is one of the least toxic (but is still in the most toxic genus of poison frogs). It is nonetheless lethal even though it has a charming appearance.

It can contain enough poison to render predators who try to eat it unable to breathe. The lovely poison frog is indigenous to Central America and can be found all over Costa Rica, central Panama, and southeast Nicaragua.

24. Sea Cucumber

Sea Cucumber
Sea Cucumber
Scientific Name Holothuroidea
Size Varies, up to 3 feet
Habitat Marine, found in all oceans
Location Worldwide, in both shallow and deep waters
Danger Level Low Toxic
Number of Deaths in a year  No information

Because of the toxins they contain, particularly holothurin, and because of their frequently impressive protective mechanisms, sea cucumbers are frequently overlooked by the majority of marine predators.

Although they are not affected by their toxins, they are nonetheless prey for some highly specialized predators, such as the large mollusks Tonna galea and Tonna perdix, which paralyze them with a potent poison before consuming them whole.

25. Black-Legged Poison Dart Frog

Black-Legged Poison Dart Frog
Black-Legged Poison Dart Frog
Scientific Name Phyllobates bicolor
Size 2.5-5 cm (1-2 inches)
Habitat Rainforest
Location Colombia and Ecuador
Danger Level Highly Toxic
Number of Deaths in a year  No information

You may have noticed the black-legged poison dart frog (Phyllobates bicolor), which looks identical to the golden dart frog.

They both belong to a group of three species of frogs, including the kokoe poison dart frog, which carries a toxin used by humans to make poison darts; therefore, they share this distinction.

Experts believe this frog’s toxin is potent enough to kill people, despite being slightly smaller, more slender, and weaker than the toxin of the golden dart frog. The black-legged poison dart frog, which lives in Colombia, is endangered due to habitat degradation.

26. Ocean Sunfish

Ocean Sunfish
Ocean Sunfish
Scientific Name Mola mola
Size Up to 10 feet (3.3 m) long
Habitat Open ocean near the surface
Location Found in tropical and temperate oceans worldwide
Danger Level Low
Number of Deaths in a year  No information

Ocean sunfish are foraging predators who eat a range of foods, but their favorite target is jellyfish.

Jellyfishes are almost entirely composed of water and are deficient in calories/nutrients; hence a fish as huge as the ocean sunfish must consume a significant number of jellyfish to maintain its weight.

They have an incredibly fast growth rate and can gain hundreds of pounds in a year, so these jellyfish experts are constantly on the lookout.

Adults are too huge to be threatened by any but the largest potential predators; however, sea lions, killer whales, and large sharks devour medium-sized individuals.

27. Porcupinefish

Scientific Name Diodon holocanthus
Size Up to 50 cm (20 in)
Habitat Tropical and subtropical waters worldwide
Location Atlantic, Indian, and Pacific ocean
Danger Level Low
Number of Deaths in a year  No information

Porcupinefish may inflate their bodies by eating water or air, making them rounder. Its increase in size (nearly doubling vertically) limits prospective predators to species with much larger mouths.

Sharp spines that spread outwards when the fish is expanded give a second protection mechanism. Several species are dangerous because they contain tetrodotoxin in their internal organs like the ovaries and liver.

This poison has a potency of at least 1200 times that of cyanide. Many species of bacteria found in the fish’s food manufacture the poison.

28. Grouper

Scientific Name Epinephelus spp.
Size 30-40 inches
Habitat Coral reefs and rocky bottoms
Location Tropical and subtropical oceans, Africa, Central America, North America, and South America
Danger Level Low to moderate (depending on species)
Number of Deaths in a year  No information

The huge Goliath grouper, the largest grouper, can grow to be 8 feet long and weigh over 800 pounds. The Coney is the smallest, growing to approximately a foot in length and weighing about a pound.

Carnivores and groupers frequently consume smaller fish, such as other groupers, and crustaceans, such as shrimp and lobsters. Little sea turtles are eaten by large groupers, such as the Goliath grouper.

Sharks, king mackerels, and moray eels eat groupers, but the only predator that can consistently handle a fish the size of an adult Goliath grouper is a human.

29. Phantasmal Poison Frog

Scientific Name Epipedobates tricolor
Size 2.5 – 3 cm
Habitat Tropical rainforests
Location Central and South America
Danger Level Highly toxic
Number of Deaths in a year  No information

The phantasmal poison frog (Epipedobates tricolor) is not only stunning but also quite a little. It only develops to approximately a half-inch to an inch and a half in length.

But don’t be fooled by his diminutive height. The poison carried by the phantasmal poison frog is lethal to an adult human.

Scientists have investigated the possibility of developing a non-addictive analgesic more strong than morphine using epibatidine, a natural alkaloid that is the potent toxin of this frog.

While promising, scientists believe epibatidine may be too hazardous for people.

30. Poisonous Caterpillars

Poisonous Caterpillars
Poisonous Caterpillars
Scientific Name Lonomia obliqua, or many other poisonous caterpillars
Size 4-5 cm in length
Habitat Tropical and subtropical forests
Location South America (Brazil, Argentina, Uruguay)
Danger Level High (potentially lethal)
Number of Deaths in a year  Up to 500 were reported in Brazil (1990-2005)

The poison in the caterpillar’s skin was discovered to include powerful anti-clotting properties. This anti-clotting substance would bind to another protein in the body’s cells, causing them to leak since blood cannot clot.

This internal bleeding would “bruise blood” on the surrounding tissue. Internal bleeding spreads through the organs, eventually resulting in compression and brain death. This accounts for at least 500 deaths caused by L. obliqua caterpillar contact.

To experience the serious symptoms caused by the poisons, a human victim would probably need to be stung at least 20 to 100 times because each sting only injects a minute amount of poison.

In conclusion, many different kinds of poisonous animals exist, some of which are quite dangerous to humans.

Each of these creatures, from the tiny but deadly dart frog to the terrifying Blue-ringed octopus, has its own arsenal of toxins and defense mechanisms that it can deploy to inflict serious harm or even kill its prey.

Being aware of and preparing for the potential dangers posed by these creatures is essential. Do not interact with or eat any of these species; instead, rush to the hospital if you think you may have been poisoned.

From a safe distance, these creatures might be interesting to watch, but they can represent a serious risk to human life and health.


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